Applications:
Pharmaceuticals, e.g. analgesics, antiinflammatory drugs, antidepressants, herbicides, immunosuppressants, USP L1, suitable for LC-MS.
Similar phases:
Zorbax® Extend C18, Synergi™ Max RP, Phenomenex Luna® C18 (2), Waters Xterra® RP18 / MS C18, Inertsil® ODS III, Purospher® RP-18, Star RP-18.
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For protection of your main HPLC column from contamination, it is recommended to use guard columns. These short columns are placed into a guard column holder. The guard column holder in combination with a guard column inside is installed between the injector and the HPLC column. This installation prevents chemical impurities to reach the main column. Because a contamination could form an irreversible bond with the column packing material (stationary phase) and this can result in shorter column life. If you want to prolong the lifetime of your main column, then these short columns can help you.
Further HPLC columns from Macherey-Nagel available on request.
The ideal phase for overall sophisticated analytical separations
This high density phase with its endcapping suppresses any unwanted polar interactions between the silica surface and the sample, which makes “Gravity” particularly suitable for the separation of basic and other ionizable analytes.
Eigenschappen:
Recommended application(s):
Partikel grootte | 3 µm |
Zuillengte | 250 mm |
Kolom binnendiameter | 4 mm |
Kolomvolume | 3.15 ml |
Endcapped | ja |
Eluent in kolom | Acetonitrile - Water |
Fase | C18 Gravity |
Surface chemistry | Base deactivated (BDS), High density octadecyl (C18, ODS) modification |
USP lijst | L1 |
Scheidingsprincipe | Reversed phase (RP) |
Zuilvorm | Analytical separation column |
Zuiltype | HPLC column |
Partikel soort | Fully porous particles (FPP) |
Specifiek oppervlak volgens BET | 340 m²/g |
Poriënvolume | 0.9 ml/g |
Poriëngr. | 110 Å |
Temperatuurstabiliteit | 60 °C |
Drukstabiliteit | 600 bar |
pH-stabiliteit | 1,0-11,0 |
Aanbevolen toepassing(en) | Analgesics, Antidepressants, Antiinflammatory drugs, Applications at pH extremes (1-11), Herbicides, Ideal for method development, Immunosuppressants, Pharmaceuticals, Phytopharmaceuticals |
Vergelijkbare fasen | NUCLEOSIL® C18 HD Zorbax® Extend C18 Synergi™ Max RP Inertsil® ODS III Luna® C18(2) Xterra® RP18 / MS C18 Purospher® Star RP-18 Gemini® Hypersil™ BDS |
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NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. We offer two phases NUCLEODUR® Gravity which is ideal for sophisticated analytical separations and NUCLEODUR® ec suitable for routine HPLC analysis.