antidesmogleína 1/2 monoclonal de ratón, DG 3.10, 0,2 ml
REF 1NP0.1
€ 132,31
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antidesmogleína 1/2 monoclonal de ratón, DG 3.10, 0,2 ml
Información del producto
P-frases: P261 P280 P302+P352 P333+P313
H-frases: H317
Código hs: 30021500
Marca: PROGEN
anti-Desmoglein 1/2 mouse , monoclonal, DG 3.10, 50 µg/ml, affinity purified (made by PROGEN), Density (D) ~1 g/cm³, Boiling point (bp) ~100 °C, Storage temp. +4 °C
This antibody portfolio includes a wide range of tissue- & tumor-specific primary antibodies for basic research, product development and analysis of a variety of biological questions. The monoclonal antibodies are perfectly applicable for all cell or tissue biology studies and for the analysis of predictive markers in research.
- High epitope affinity
- Highly specific detection of the target protein
- Unconjugated
- Suitable for e.g. western blot, immunoprecipitation, ELISA & immunofluorescence
anti-Desmoglein 1/2 mouse monoclonal, DG 3.10 50 μg/ml, monoclonal, affinity purified
DG 3.10 recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells; does not react with cells containing plaque-bearing junctions of non-desmosomal type.
Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas.
Polypeptide reacting: Mr 165 000 Desmoglein, 'band 3' polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ('RUD') of the cytoplasmic C-terminal part of the polypeptide.
Reactivity on cultured cell lines: A-431, MDBK.
Host: mouse
Antibody type: monoclonal
Isotype: IgG1
Clone: DG 3.10
Immunogen: 'band 3' polypeptide of isolated desmosomes from bovine muzzle epidermis
UniprotID: Q02413 (human), D3ZM39 (rat), Q03763 (bovine)
Synonym: desmoglein-1, cadherin family member 4, desmosomal glycoprotein 1, DG1, DGI, pemphigus foliaceus antigen, DSG1, CDHF4
Conjugate: unconjugated
Purification: affinity chromatography
Intended use: research use only
Application: ICC/IF, IHC, WB
Reactivity: bovine, human, rat
Toepassing
Immunocytochemistry (ICC): Assay dependent
Immunohistochemistry (IHC) - frozen: 1:10-1:100 (0.5-5 μg/ml)
Immunohistochemistry (IHC) - paraffin: 1:10-1:100 (0.5-5 μg/ml, microwave treatment recommended)
Western Blot (WB): 1:2000-1:4000 (12,5 ng/ml - 25 ng/ml)
IHC of rat colon with anti-Desmocollin 1/2 (1:100, © PROGEN in cooperation with Uniklinik Heidelberg, Dr. Jochen Heß)
IHC of rat heart with anti-Desmocollin 1/2 (1:50, © PROGEN in cooperation with Uniklinik Heidelberg, Dr. Jochen Heß)
IHC of rat tail with anti-Desmocollin 1/2 (1:50, © PROGEN in cooperation with Uniklinik Heidelberg, Dr. Jochen Heß)
Geen medisch hulpmiddel / Geen ivD-product
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