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Urea crosslinker – C4-arm, NHS ester (DSBU, BuUrBU) 100 mg

Urea crosslinker – C4-arm, NHS ester (DSBU, BuUrBU) 100 mg

SKU PCL008_0100
€ 247,93
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Urea crosslinker – C4-arm, NHS ester (DSBU, BuUrBU) 100 mg
Product Details
P-phrases: P261 Avoid breathing dust., P232 Protect from moisture., P280 Wear protective gloves/ protective clothing/ eye protection., P302 + P352 IF ON SKIN: Wash with plenty of water., P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
H-phrases: H315 Causes skin irritation., H319 Causes serious eye irritation., H332 Harmful if inhaled., H335 May cause respiratory irritation.
CAS number: 1240387-33-0
Chemical formulas: C17H22N4O9
Molar mass g/mol: 426,38
HS code: 292800
Packaging: 0,1 g
Brand: CF Plus Chemicals

Ureido-4,4´-dibutyric acid bis(hydroxysuccinimide) ester, also known as DSBU or BuUrBU, is the longest length version of MS-cleavable urea-based lysine-lysine reactive homobifunctional cross-linkers. At neutral or slightly basic pH, it irreversibly crosslinks the neighbouring lysine groups. The presence of the symmetrical urea moiety which is prone to collision-induced dissociation allows to perform unambiguous distinguishing of crosslinks in tandem CID-MS experiments.

The urea-based MS-cleavable crosslinkers are based on the concept pioneered by Prof. Dr. Andrea Sinz of the Halle University.

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