GHK-Cu Copper Peptiden 5g

GHK-Cu is a copper tripeptide with the primary structure Gly-L-His-L-Lys, naturally occurring in the human body. It is a powerful chelator with high affinity for copper(II) (Cu²⁺), forming a stable complex known as GHK-Cu. First isolated from human plasma, it is also found in saliva and urine.

Biological functions and activity
GHK-Cu plays a crucial role in various biological processes:
- Wound healing – promotes cell repair and stimulates fibroblasts.
- Stimulation of collagen and glycosaminoglycan – improves skin structure and elasticity.
- Angiogenesis – supports new blood vessel growth.
- Anti-inflammatory & antioxidant – protects cells from free radical damage.
- Immune modulation – attracts immune cells and enhances recovery.
- Gene expression – studies show GHK-Cu can modulate the expression of hundreds of genes.

Applications
GHK-Cu is widely used across sectors:
Cosmetics & skincare

• Anti-aging creams and serums
• Repair and regeneration products
• Products supporting wound and scar healing

Biomedical & pharmaceutical research

• Wound healing and tissue repair studies
• Research on gene expression and cell biology

Professional & industrial use

• High-quality ingredient for cosmetic formulations
• Reference material for analytical research

Structure & stability
The GHK-Cu complex has been extensively studied with X-ray crystallography, NMR, and spectroscopy.

• Cu²⁺ binds to the imidazole nitrogen of histidine, the α-amino nitrogen of glycine, and the nitrogen of the peptide bond between glycine and histidine.
• Stability: dissociation constant log₁₀(K) = 16.44, higher than similar copper complexes.
• The carboxyl oxygen of lysine may also contribute to stability.

Benefits of GHK-Cu
- Highly stable copper complex
- Non-toxic copper transport to cells
- Broad applications in cosmetics & pharma research
- Strong biological activity confirmed in studies

Product details

• Name: GHK-Cu (copper peptide)
• Structure: Gly-L-His-L-Lys with Cu²⁺ binding
• Form: Pure tripeptide-copper complex
• Application: Cosmetic formulations, research & development
• Quality: Extra pure, professional grade