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SMCC crosslinker 1 g

SMCC crosslinker 1 g

SKU PCL025_1
€ 74,38
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SMCC crosslinker 1 g
Product Details
P-phrases: P261 Avoid breathing dust., P264 Wash contaminated skin thoroughly after handling., P280 Wear protective gloves/protective clothing/eye protection., P302 + P352 IF ON SKIN: Wash with plenty of water., P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
H-phrases: H315 Causes skin irritation., H319 Causes serious eye irritation., H335 May cause respiratory irritation.
CAS number: 71875-81-5
Chemical formulas: C16H18N2O6
Molar mass g/mol: 334,33
HS code: 291712
Packaging: 1 g
Brand: CF Plus Chemicals

4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester (SMCC) is a heterobifunctional cross-linking reagent containing amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). The second coupling is specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). SMCC contains nine atom linker. An extended aliphatic spacer stabilizes the maleimide prior to coupling compared to aromatic spacers.

4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester (SMCC) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

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