anti-Keratin K6 mouse monoclonal, KA12, 1 ml

This antibody portfolio includes a wide range of tissue- & tumor-specific primary antibodies for basic research, product development and analysis of a variety of biological questions. The monoclonal antibodies are perfectly applicable for all cell or tissue biology studies and for the analysis of predictive markers in research.

Ks6.KA12 represents an excellent marker for non-keratinized squamous epithelia and proliferating cells of epidermis (e.g. within psoriatic lesions).

Polypeptide reacting: Mr 56,000 polypeptide (keratin K6; formerly also designated cytokeratin 6) of human squamous epithelia.

Tissues and tumors specifically detected: the antibody is suitable for discrimination of keratinizing and non-keratinizing squamous cell carcinoma versus e.g. poorly differentiated adenocarcinoma.

Host: mouse
Antibody type: monoclonal
Isotype: IgG1
Clone: Ks6.KA12
Immunogen: keratin K6 of human callus cytoskeletal preparation
UniprotID: P02538 (human), P50446 (mouse), Q4FZU2 (rat)
Synonym: keratin, type II cytoskeletal 6A, cytokeratin-6A, CK-6A, cytokeratin-6D, CK-6D, keratin-6A, K6A, type-II keratin Kb6, allergen Hom s 5, KRT6A, K6A, KRT6D
Conjugate: unconjugated
Purificatio:n affinity chromatography
Intended use: research use only
Application: IHC, WB
Reactivity: human, mouse, rat

Immunohistochemistry (IHC) - frozen: 1:5-1:50 (1-10 μg/ml)
Immunohistochemistry (IHC) - paraffin: 1:5-1:50 (1-10 μg/ml, microwave treatment recommended)
Western Blot (WB): assay dependent