Irreversible, strong and highly selective inhibition of cysteine protease (e. g. papain, bromelain, ficin, cathepsin B, H and L, tumor-cathepsin, calpain etc.). Does not inhibit serine proteases except trypsin.
Low toxicity, high cell permeability and stability against reducing reagents makes E-64 an excellent alternative to leupeptin or antipain.
Working concentration: 1-10 µM.
Appearance | white powder |
Assay (HPLC) | ≥99 % |
Specific rotation [α]20D (in 0,1 N HCl) | +21° to +26° |